Oncotarget a primarily oncology-focused, peer-reviewed, open access, weekly journal aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science. Its scope is unique. The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. The term was introduced in the inaugural Editorial Introducing OncoTarget.
What Is a Sentinel Node Biopsy?
Sentinel Node Biopsy: Uses, Procedure, Results
The sentinel lymph node biopsy is basically a staging technique for invasive cancer, and also provides useful information to guide subsequent therapies. However, it should be noted that not all clinics practice nor recommend the technique. It is the sort of procedure that may be called for in unique situations. The basic concept is that the sentinel lymph node is the first to receive lymphatic drainage, and in theory, the first lymph node into which a malignant tumor will metastize. Therefore, a negative status for the sentinel lymph node can just about guartantee that the other nodes are also clear.
Sentinel Node Biopsy
Breast cancer — patients having either breast-conserving surgery or a mastectomy are candidates for sentinel lymph node dissection SLND if there is no palpable lymph node disease or clinical evidence of axillary lymph node disease. The presence of breast cancer in axillary lymph nodes changes the staging of the disease, contributes to the prognosis of recurrence and survival, and impacts the decision regarding chemotherapy, radiation, and hormonal therapy. This means that a correctly identified sentinel lymph node does not contain cancer but there is cancer present in higher level nodes. Approximately 90 minutes before the start of the procedure injects a radionuclide solution into the breast.
A sentinel lymph node biopsy SLNB is a type of surgery. It can help your doctor determine the stage of your breast cancer, including whether or not it has spread outside of your breast. The knowledge your doctor gains from this procedure will guide your treatment plan.